I'm not familiar with the artist but this looks like a print that does not date to the 17th Century, so much as referencing it. I would have to research to yield a formal appraisal but my gut feeling is this is probably worth around $45 retail.
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Mayflower ship by HAmuth La sirene 1650
M
Marc's Expert Appraisal
ANA-Certified Numismatist · Hudson Valley Numismatics
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